Professor Michael Kalichman (U.C. San Diego) discusses the promise of science within the context of the profound ethical issues that arise with the application of new technologies. Answering those questions depends on both critical philosophical inquiry and good data. Unfortunately, the reliability of the science is in question. Theoretical and empirical investigations have caused many to believe that science now faces a reproducibility crisis: Much that is published by one team of scientists cannot be reproduced by another. Kalichman analyzes a number of issues, including the magnitude of this crisis, factors contributing to research findings that are not reproducible, and identifying strategies that will promote the rigor and reproducibility of science.